1vr1
From Proteopedia
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===Specifity for Plasminogen Activator Inhibitor-1=== | ===Specifity for Plasminogen Activator Inhibitor-1=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1vr1]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VR1 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Hirudin|Hirudin]] | ||
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:010543954</ref><references group="xtra"/> |
| + | [[Category: Hirudo medicinalis]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| + | [[Category: Thrombin]] | ||
[[Category: Bode, W.]] | [[Category: Bode, W.]] | ||
[[Category: Dekker, R J.]] | [[Category: Dekker, R J.]] | ||
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[[Category: Pannekoek, H.]] | [[Category: Pannekoek, H.]] | ||
[[Category: Stoop, A A.]] | [[Category: Stoop, A A.]] | ||
| + | [[Category: Blood clotting-hydrolase inhibitor complex]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:17:03 2009'' | ||
Revision as of 07:30, 27 July 2012
Contents |
Specifity for Plasminogen Activator Inhibitor-1
Template:ABSTRACT PUBMED 10543954
About this Structure
1vr1 is a 3 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Dekker RJ, Eichinger A, Stoop AA, Bode W, Pannekoek H, Horrevoets AJ. The variable region-1 from tissue-type plasminogen activator confers specificity for plasminogen activator inhibitor-1 to thrombin by facilitating catalysis: release of a kinetic block by a heterologous protein surface loop. J Mol Biol. 1999 Oct 29;293(3):613-27. PMID:10543954 doi:10.1006/jmbi.1999.3178
