1nwl
From Proteopedia
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{{STRUCTURE_1nwl| PDB=1nwl | SCENE= }} | {{STRUCTURE_1nwl| PDB=1nwl | SCENE= }} | ||
===Crystal structure of the PTP1B complexed with SP7343-SP7964, a pTyr mimetic=== | ===Crystal structure of the PTP1B complexed with SP7343-SP7964, a pTyr mimetic=== | ||
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{{ABSTRACT_PUBMED_12733877}} | {{ABSTRACT_PUBMED_12733877}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Insulin resistance, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176885 176885]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1nwl]] is a 1 chain structure of [[Proten tyrosine phosphatase]] and [[Tyrosine phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NWL OCA]. | |
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| + | ==See Also== | ||
| + | *[[Proten tyrosine phosphatase|Proten tyrosine phosphatase]] | ||
| + | *[[Tyrosine phosphatase|Tyrosine phosphatase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012733877</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
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[[Category: Simmons, R L.]] | [[Category: Simmons, R L.]] | ||
[[Category: Waight, A.]] | [[Category: Waight, A.]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Protein-small molecule inhibitor complex]] | [[Category: Protein-small molecule inhibitor complex]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:17:24 2009'' | ||
Revision as of 07:30, 27 July 2012
Contents |
Crystal structure of the PTP1B complexed with SP7343-SP7964, a pTyr mimetic
Template:ABSTRACT PUBMED 12733877
About this Structure
1nwl is a 1 chain structure of Proten tyrosine phosphatase and Tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Erlanson DA, McDowell RS, He MM, Randal M, Simmons RL, Kung J, Waight A, Hansen SK. Discovery of a new phosphotyrosine mimetic for PTP1B using breakaway tethering. J Am Chem Soc. 2003 May 14;125(19):5602-3. PMID:12733877 doi:10.1021/ja034440c
