1nce
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:1nce.png|left|200px]] | [[Image:1nce.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_1nce", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_1nce| PDB=1nce | SCENE= }} | {{STRUCTURE_1nce| PDB=1nce | SCENE= }} | ||
===Crystal structure of a ternary complex of E. coli thymidylate synthase D169C with dUMP and the antifolate CB3717=== | ===Crystal structure of a ternary complex of E. coli thymidylate synthase D169C with dUMP and the antifolate CB3717=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_12702803}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 12702803 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_12702803}} | {{ABSTRACT_PUBMED_12702803}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1nce]] is a 2 chain structure of [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli,_escherichia_coli_o157:h7 Escherichia coli, escherichia coli o157:h7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCE OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Thymidylate synthase|Thymidylate synthase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012702803</ref><references group="xtra"/> |
| - | [[Category: Escherichia coli, | + | [[Category: Escherichia coli, escherichia coli o157:h7]] |
[[Category: Thymidylate synthase]] | [[Category: Thymidylate synthase]] | ||
[[Category: Birdsall, D L.]] | [[Category: Birdsall, D L.]] | ||
| Line 31: | Line 22: | ||
[[Category: Asymmetric dimer]] | [[Category: Asymmetric dimer]] | ||
[[Category: Beta-sheet interface]] | [[Category: Beta-sheet interface]] | ||
| + | [[Category: Biosynthetic protein]] | ||
[[Category: Protein-dump-cofactor analog complex]] | [[Category: Protein-dump-cofactor analog complex]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:44:15 2009'' | ||
Revision as of 08:05, 27 July 2012
Contents |
Crystal structure of a ternary complex of E. coli thymidylate synthase D169C with dUMP and the antifolate CB3717
Template:ABSTRACT PUBMED 12702803
About this Structure
1nce is a 2 chain structure of Thymidylate synthase with sequence from Escherichia coli, escherichia coli o157:h7. Full crystallographic information is available from OCA.
See Also
Reference
- Birdsall DL, Finer-Moore J, Stroud RM. The only active mutant of thymidylate synthase D169, a residue far from the site of methyl transfer, demonstrates the exquisite nature of enzyme specificity. Protein Eng. 2003 Mar;16(3):229-40. PMID:12702803
