3mvl
From Proteopedia
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{{STRUCTURE_3mvl| PDB=3mvl | SCENE= }} | {{STRUCTURE_3mvl| PDB=3mvl | SCENE= }} | ||
===P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7K=== | ===P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7K=== | ||
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{{ABSTRACT_PUBMED_20804198}} | {{ABSTRACT_PUBMED_20804198}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3mvl]] is a 2 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MVL OCA]. | |
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| + | ==See Also== | ||
| + | *[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020804198</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mitogen-activated protein kinase]] | [[Category: Mitogen-activated protein kinase]] | ||
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[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:47:54 2010'' | ||
Revision as of 08:30, 27 July 2012
Contents |
P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7K
Template:ABSTRACT PUBMED 20804198
About this Structure
3mvl is a 2 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Liu C, Lin J, Wrobleski ST, Lin S, Hynes J, Wu H, Dyckman AJ, Li T, Wityak J, Gillooly KM, Pitt S, Shen DR, Zhang RF, McIntyre KW, Salter-Cid L, Shuster DJ, Zhang H, Marathe PH, Doweyko AM, Sack JS, Kiefer SE, Kish KF, Newitt JA, McKinnon M, Dodd JH, Barrish JC, Schieven GL, Leftheris K. Discovery of 4-(5-(cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-N-propylpyrrolo[ 1,2-f][1,2,4]triazine-6-carboxamide (BMS-582949), a clinical p38alpha MAP kinase inhibitor for the treatment of inflammatory diseases. J Med Chem. 2010 Sep 23;53(18):6629-39. PMID:20804198 doi:10.1021/jm100540x
