3ika
From Proteopedia
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{{STRUCTURE_3ika| PDB=3ika | SCENE= }} | {{STRUCTURE_3ika| PDB=3ika | SCENE= }} | ||
===Crystal Structure of EGFR 696-1022 T790M Mutant Covalently Binding to WZ4002=== | ===Crystal Structure of EGFR 696-1022 T790M Mutant Covalently Binding to WZ4002=== | ||
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{{ABSTRACT_PUBMED_20033049}} | {{ABSTRACT_PUBMED_20033049}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3ika]] is a 2 chain structure of [[Epidermal Growth Factor Receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IKA OCA]. | |
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| + | ==See Also== | ||
| + | *[[Epidermal Growth Factor Receptor|Epidermal Growth Factor Receptor]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020033049</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Eck, M J.]] | [[Category: Eck, M J.]] | ||
[[Category: Yun, C H.]] | [[Category: Yun, C H.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Cell membrane]] | [[Category: Cell membrane]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
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[[Category: Tumor suppressor]] | [[Category: Tumor suppressor]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
| - | [[Category: Ubl conjugation]] | ||
[[Category: Wz-4002]] | [[Category: Wz-4002]] | ||
[[Category: Wz4002]] | [[Category: Wz4002]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 13 14:03:38 2010'' | ||
Revision as of 08:44, 27 July 2012
Contents |
Crystal Structure of EGFR 696-1022 T790M Mutant Covalently Binding to WZ4002
Template:ABSTRACT PUBMED 20033049
About this Structure
3ika is a 2 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Zhou W, Ercan D, Chen L, Yun CH, Li D, Capelletti M, Cortot AB, Chirieac L, Iacob RE, Padera R, Engen JR, Wong KK, Eck MJ, Gray NS, Janne PA. Novel mutant-selective EGFR kinase inhibitors against EGFR T790M. Nature. 2009 Dec 24;462(7276):1070-4. PMID:20033049 doi:10.1038/nature08622
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Eck, M J. | Yun, C H. | Atp-binding | Cell membrane | Disease mutation | Disulfide bond | Egfr | Glycoprotein | Isopeptide bond | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Receptor | Secreted | T790m | Transferase | Transmembrane | Tumor suppressor | Tyrosine-protein kinase | Wz-4002 | Wz4002
