1e8x
From Proteopedia
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[[Image:1e8x.png|left|200px]] | [[Image:1e8x.png|left|200px]] | ||
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{{STRUCTURE_1e8x| PDB=1e8x | SCENE= }} | {{STRUCTURE_1e8x| PDB=1e8x | SCENE= }} | ||
===STRUCTURAL INSIGHTS INTO PHOSHOINOSITIDE 3-KINASE ENZYMATIC MECHANISM AND SIGNALLING=== | ===STRUCTURAL INSIGHTS INTO PHOSHOINOSITIDE 3-KINASE ENZYMATIC MECHANISM AND SIGNALLING=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Phosphoinositide 3-Kinases]] | + | *[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]] |
| + | *[[Phsphatidylinositol 3-kinase|Phsphatidylinositol 3-kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:011090628</ref><ref group="xtra">PMID:010580505</ref><ref group="xtra">PMID:020081827</ref><references group="xtra"/> |
[[Category: Phosphatidylinositol 3-kinase]] | [[Category: Phosphatidylinositol 3-kinase]] | ||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
Revision as of 08:59, 27 July 2012
Contents |
STRUCTURAL INSIGHTS INTO PHOSHOINOSITIDE 3-KINASE ENZYMATIC MECHANISM AND SIGNALLING
Template:ABSTRACT PUBMED 11090628
About this Structure
1e8x is a 1 chain structure of Phosphoinositide 3-Kinases with sequence from Sus scrofa. This structure supersedes the now removed PDB entry 1qmm. Full crystallographic information is available from OCA.
See Also
Reference
- Walker EH, Pacold ME, Perisic O, Stephens L, Hawkins PT, Wymann MP, Williams RL. Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine. Mol Cell. 2000 Oct;6(4):909-19. PMID:11090628
- Walker EH, Perisic O, Ried C, Stephens L, Williams RL. Structural insights into phosphoinositide 3-kinase catalysis and signalling. Nature. 1999 Nov 18;402(6759):313-20. PMID:10580505 doi:10.1038/46319
- Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI, Gorrec F, Hon WC, Liu Y, Rommel C, Gaillard P, Ruckle T, Schwarz MK, Shokat KM, Shaw JP, Williams RL. The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors. Nat Chem Biol. 2010 Feb;6(2):117-24. PMID:20081827 doi:10.1038/nchembio.293
