2cib
From Proteopedia
(New page: 200px<br /> <applet load="2cib" size="450" color="white" frame="true" align="right" spinBox="true" caption="2cib, resolution 1.50Å" /> '''HIGH THROUGHPUT SCR...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2CIB is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]] with HEM and CM6 as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.70 1.14.13.70]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CIB OCA]]. | + | 2CIB is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]] with HEM and CM6 as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Sterol_14-demethylase Sterol 14-demethylase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.70 1.14.13.70]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CIB OCA]]. |
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| + | [[Category: Sterol 14-demethylase]] | ||
[[Category: Kim, Y.]] | [[Category: Kim, Y.]] | ||
[[Category: Kries, J.P.Von.]] | [[Category: Kries, J.P.Von.]] | ||
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[[Category: sterol biosynthesis]] | [[Category: sterol biosynthesis]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:10:48 2007'' |
Revision as of 12:06, 30 October 2007
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HIGH THROUGHPUT SCREENING AND X-RAY CRYSTALLOGRAPHY ASSISTED EVALUATION OF SMALL MOLECULE SCAFFOLDS FOR CYP51 INHIBITORS
About this Structure
2CIB is a [Single protein] structure of sequence from [Mycobacterium tuberculosis] with HEM and CM6 as [ligands]. Active as [Sterol 14-demethylase], with EC number [1.14.13.70]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Page seeded by OCA on Tue Oct 30 14:10:48 2007
Categories: Mycobacterium tuberculosis | Single protein | Sterol 14-demethylase | Kim, Y. | Kries, J.P.Von. | Podust, L.M. | Waterman, M.R. | Yermalitskaya, L.V. | CM6 | HEM | Heme | Heme lipid synthesis | Metal-binding | Monooxygenase | Nadp | Oxidoreductase | Protein-inhibitor complex | Steroid biosynthesis | Sterol biosynthesis
