2flr
From Proteopedia
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[[Image:2flr.png|left|200px]] | [[Image:2flr.png|left|200px]] | ||
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{{STRUCTURE_2flr| PDB=2flr | SCENE= }} | {{STRUCTURE_2flr| PDB=2flr | SCENE= }} | ||
===Novel 5-Azaindole Factor VIIa Inhibitors=== | ===Novel 5-Azaindole Factor VIIa Inhibitors=== | ||
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{{ABSTRACT_PUBMED_16621549}} | {{ABSTRACT_PUBMED_16621549}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Factor VII deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Myocardial infarction, decreased susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2flr]] is a 3 chain structure of [[Factor VIIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FLR OCA]. | |
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| + | ==See Also== | ||
| + | *[[Factor VIIa|Factor VIIa]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016621549</ref><references group="xtra"/> |
[[Category: Coagulation factor VIIa]] | [[Category: Coagulation factor VIIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Yu, C.]] | [[Category: Yu, C.]] | ||
[[Category: 5-azaindole inhibitor]] | [[Category: 5-azaindole inhibitor]] | ||
| + | [[Category: Hydrolase-blood clotting complex]] | ||
[[Category: S1 site]] | [[Category: S1 site]] | ||
[[Category: Short hydrogen bond]] | [[Category: Short hydrogen bond]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 02:48:34 2009'' | ||
Revision as of 09:26, 27 July 2012
Contents |
Novel 5-Azaindole Factor VIIa Inhibitors
Template:ABSTRACT PUBMED 16621549
About this Structure
2flr is a 3 chain structure of Factor VIIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Riggs JR, Hu H, Kolesnikov A, Leahy EM, Wesson KE, Shrader WD, Vijaykumar D, Wahl TA, Tong Z, Sprengeler PA, Green MJ, Yu C, Katz BA, Sanford E, Nguyen M, Cabuslay R, Young WB. Novel 5-azaindole factor VIIa inhibitors. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3197-200. Epub 2006 Apr 18. PMID:16621549 doi:10.1016/j.bmcl.2006.03.049
Categories: Coagulation factor VIIa | Homo sapiens | Green, M J. | Hu, H. | Katz, B A. | Kolesnikov, A. | Leahy, E M. | Riggs, J R. | Shrader, W D. | Sprengeler, P A. | Tong, Z. | Vijaykumar, D. | Wahl, T A. | Wesson, K E. | Young, W B. | Yu, C. | 5-azaindole inhibitor | Hydrolase-blood clotting complex | S1 site | Short hydrogen bond
