3ril
From Proteopedia
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| - | [[Image:3ril. | + | [[Image:3ril.png|left|200px]] |
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{{STRUCTURE_3ril| PDB=3ril | SCENE= }} | {{STRUCTURE_3ril| PDB=3ril | SCENE= }} | ||
===The acid beta-glucosidase active site exhibits plasticity in binding 3,4,5,6-tetrahydroxyazepane-based inhibitors: implications for pharmacological chaperone design for gaucher disease=== | ===The acid beta-glucosidase active site exhibits plasticity in binding 3,4,5,6-tetrahydroxyazepane-based inhibitors: implications for pharmacological chaperone design for gaucher disease=== | ||
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{{ABSTRACT_PUBMED_22047104}} | {{ABSTRACT_PUBMED_22047104}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3ril]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RIL OCA]. | + | [[3ril]] is a 4 chain structure of [[Acid-beta-glucosidase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RIL OCA]. |
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| + | ==See Also== | ||
| + | *[[Acid-beta-glucosidase|Acid-beta-glucosidase]] | ||
==Reference== | ==Reference== | ||
Revision as of 10:00, 27 July 2012
Contents |
The acid beta-glucosidase active site exhibits plasticity in binding 3,4,5,6-tetrahydroxyazepane-based inhibitors: implications for pharmacological chaperone design for gaucher disease
Template:ABSTRACT PUBMED 22047104
About this Structure
3ril is a 4 chain structure of Acid-beta-glucosidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Orwig SD, Tan YL, Grimster NP, Yu Z, Powers ET, Kelly JW, Lieberman RL. Binding of 3,4,5,6-tetrahydroxyazepanes to the acid-beta-glucosidase active site: implications for pharmacological chaperone design for Gaucher disease. Biochemistry. 2011 Dec 13;50(49):10647-57. Epub 2011 Nov 14. PMID:22047104 doi:10.1021/bi201619z
