2ant
From Proteopedia
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===THE 2.6 A STRUCTURE OF ANTITHROMBIN INDICATES A CONFORMATIONAL CHANGE AT THE HEPARIN BINDING SITE=== | ===THE 2.6 A STRUCTURE OF ANTITHROMBIN INDICATES A CONFORMATIONAL CHANGE AT THE HEPARIN BINDING SITE=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2ant]] is a 2 chain structure of [[Antithrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANT OCA]. | |
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| + | ==See Also== | ||
| + | *[[Antithrombin|Antithrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:009067613</ref><ref group="xtra">PMID:009692954</ref><ref group="xtra">PMID:010966821</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Abrahams, J P.]] | [[Category: Abrahams, J P.]] | ||
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[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Serpin]] | [[Category: Serpin]] | ||
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Revision as of 10:25, 27 July 2012
Contents |
THE 2.6 A STRUCTURE OF ANTITHROMBIN INDICATES A CONFORMATIONAL CHANGE AT THE HEPARIN BINDING SITE
Template:ABSTRACT PUBMED 9067613
About this Structure
2ant is a 2 chain structure of Antithrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Skinner R, Abrahams JP, Whisstock JC, Lesk AM, Carrell RW, Wardell MR. The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site. J Mol Biol. 1997 Feb 28;266(3):601-9. PMID:9067613 doi:10.1006/jmbi.1996.0798
- Alberdi E, Hyde CC, Becerra SP. Pigment epithelium-derived factor (PEDF) binds to glycosaminoglycans: analysis of the binding site. Biochemistry. 1998 Jul 28;37(30):10643-52. PMID:9692954 doi:10.1021/bi9802317
- Whisstock JC, Pike RN, Jin L, Skinner R, Pei XY, Carrell RW, Lesk AM. Conformational changes in serpins: II. The mechanism of activation of antithrombin by heparindagger. J Mol Biol. 2000 Sep 1;301(5):1287-305. PMID:10966821 doi:10.1006/jmbi.2000.3982
