1iep
From Proteopedia
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===CRYSTAL STRUCTURE OF THE C-ABL KINASE DOMAIN IN COMPLEX WITH STI-571.=== | ===CRYSTAL STRUCTURE OF THE C-ABL KINASE DOMAIN IN COMPLEX WITH STI-571.=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1iep]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IEP OCA]. | |
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| + | ==See Also== | ||
| + | *[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012154025</ref><ref group="xtra">PMID:012211034</ref><ref group="xtra">PMID:015298055</ref><references group="xtra"/> |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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[[Category: Kinase inhibitor]] | [[Category: Kinase inhibitor]] | ||
[[Category: Sti-571]] | [[Category: Sti-571]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 10:44, 27 July 2012
Contents |
CRYSTAL STRUCTURE OF THE C-ABL KINASE DOMAIN IN COMPLEX WITH STI-571.
Template:ABSTRACT PUBMED 12154025
About this Structure
1iep is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Mus musculus. Full crystallographic information is available from OCA.
See Also
Reference
- Nagar B, Bornmann WG, Pellicena P, Schindler T, Veach DR, Miller WT, Clarkson B, Kuriyan J. Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571). Cancer Res. 2002 Aug 1;62(15):4236-43. PMID:12154025
- Rockey WM, Elcock AH. Progress toward virtual screening for drug side effects. Proteins. 2002 Sep 1;48(4):664-71. PMID:12211034 doi:10.1002/prot.10186
- Veit M. [New strategies for drug development]. Berl Munch Tierarztl Wochenschr. 2004 Jul-Aug;117(7-8):276-87. PMID:15298055
