1iep

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Revision as of 10:44, 27 July 2012

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Template:STRUCTURE 1iep

Contents 1 CRYSTAL STRUCTURE OF THE C-ABL KINASE DOMAIN IN COMPLEX WITH STI-571. 2 About this Structure 3 See Also 4 Reference

CRYSTAL STRUCTURE OF THE C-ABL KINASE DOMAIN IN COMPLEX WITH STI-571.

Template:ABSTRACT PUBMED 12154025

About this Structure

1iep is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Mus musculus. Full crystallographic information is available from OCA.

See Also

• Proto-oncogene tyrosine-protein kinase

Reference

• Nagar B, Bornmann WG, Pellicena P, Schindler T, Veach DR, Miller WT, Clarkson B, Kuriyan J. Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571). Cancer Res. 2002 Aug 1;62(15):4236-43. PMID:12154025
• Rockey WM, Elcock AH. Progress toward virtual screening for drug side effects. Proteins. 2002 Sep 1;48(4):664-71. PMID:12211034 doi:10.1002/prot.10186
• Veit M. [New strategies for drug development]. Berl Munch Tierarztl Wochenschr. 2004 Jul-Aug;117(7-8):276-87. PMID:15298055