3cwe
From Proteopedia
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===PTP1B in complex with a phosphonic acid inhibitor=== | ===PTP1B in complex with a phosphonic acid inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3cwe]] is a 1 chain structure of [[Proten tyrosine phosphatase]] and [[Tyrosine phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CWE OCA]. | |
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| + | ==See Also== | ||
| + | *[[Proten tyrosine phosphatase|Proten tyrosine phosphatase]] | ||
| + | *[[Tyrosine phosphatase|Tyrosine phosphatase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018477508</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
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[[Category: Kennedy, B P.]] | [[Category: Kennedy, B P.]] | ||
[[Category: Scapin, G.]] | [[Category: Scapin, G.]] | ||
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[[Category: Diabetes]] | [[Category: Diabetes]] | ||
[[Category: Endoplasmic reticulum]] | [[Category: Endoplasmic reticulum]] | ||
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[[Category: Phosphonate]] | [[Category: Phosphonate]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protein phosphatase]] | [[Category: Protein phosphatase]] | ||
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Revision as of 11:02, 27 July 2012
Contents |
PTP1B in complex with a phosphonic acid inhibitor
Template:ABSTRACT PUBMED 18477508
About this Structure
3cwe is a 1 chain structure of Proten tyrosine phosphatase and Tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Han Y, Belley M, Bayly CI, Colucci J, Dufresne C, Giroux A, Lau CK, Leblanc Y, McKay D, Therien M, Wilson MC, Skorey K, Chan CC, Scapin G, Kennedy BP. Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3200-5. Epub 2008 Apr 29. PMID:18477508 doi:10.1016/j.bmcl.2008.04.064
