2yiq

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[[Image:2yiq.png|left|200px]]
[[Image:2yiq.png|left|200px]]
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{{STRUCTURE_2yiq| PDB=2yiq | SCENE= }}
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===STRUCTURAL ANALYSIS OF CHECKPOINT KINASE 2 IN COMPLEX WITH INHIBITOR PV1322===
===STRUCTURAL ANALYSIS OF CHECKPOINT KINASE 2 IN COMPLEX WITH INHIBITOR PV1322===
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==See Also==
==See Also==
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*[[Serine/threonine protein kinase]]
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*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]
==Reference==
==Reference==

Revision as of 11:03, 27 July 2012

Template:STRUCTURE 2yiq

Contents

STRUCTURAL ANALYSIS OF CHECKPOINT KINASE 2 IN COMPLEX WITH INHIBITOR PV1322

Template:ABSTRACT PUBMED 21907711

About this Structure

2yiq is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Lountos GT, Jobson AG, Tropea JE, Self CR, Zhang G, Pommier Y, Shoemaker RH, Waugh DS. X-ray structures of checkpoint kinase 2 in complex with inhibitors that target its gatekeeper-dependent hydrophobic pocket. FEBS Lett. 2011 Oct 20;585(20):3245-9. Epub 2011 Sep 7. PMID:21907711 doi:10.1016/j.febslet.2011.08.050
  • Lountos GT, Tropea JE, Zhang D, Jobson AG, Pommier Y, Shoemaker RH, Waugh DS. Crystal structure of checkpoint kinase 2 in complex with NSC 109555, a potent and selective inhibitor. Protein Sci. 2009 Jan;18(1):92-100. PMID:19177354 doi:10.1002/pro.16

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