1h1k
From Proteopedia
(New page: 200px<br /><applet load="1h1k" size="450" color="white" frame="true" align="right" spinBox="true" caption="1h1k, resolution 10.Å" /> '''THE BLUETONGUE VIRUS ...) |
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| - | [[Image:1h1k.gif|left|200px]]<br /><applet load="1h1k" size=" | + | [[Image:1h1k.gif|left|200px]]<br /><applet load="1h1k" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1h1k, resolution 10.Å" /> | caption="1h1k, resolution 10.Å" /> | ||
'''THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA'''<br /> | '''THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA'''<br /> | ||
==Overview== | ==Overview== | ||
| - | Double-stranded RNA (dsRNA) viruses conceal their genome from the host to | + | Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an outer surface festooned with dsRNA. This may represent a deliberate strategy to sequester dsRNA released from damaged particles to prevent host cell shutoff. |
==About this Structure== | ==About this Structure== | ||
| - | 1H1K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bluetongue_virus Bluetongue virus]. Full crystallographic information is available from [http:// | + | 1H1K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bluetongue_virus Bluetongue virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H1K OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Bluetongue virus]] | [[Category: Bluetongue virus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Burroughs, J | + | [[Category: Burroughs, J N.]] |
| - | [[Category: Diprose, J | + | [[Category: Diprose, J M.]] |
| - | [[Category: Grimes, J | + | [[Category: Grimes, J M.]] |
[[Category: Maan, S.]] | [[Category: Maan, S.]] | ||
| - | [[Category: Mertens, P | + | [[Category: Mertens, P P.C.]] |
[[Category: Meyer, A.]] | [[Category: Meyer, A.]] | ||
| - | [[Category: Stuart, D | + | [[Category: Stuart, D I.]] |
[[Category: Sutton, G.]] | [[Category: Sutton, G.]] | ||
[[Category: rna]] | [[Category: rna]] | ||
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[[Category: virus]] | [[Category: virus]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:56:21 2008'' |
Revision as of 10:56, 21 February 2008
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THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
Overview
Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an outer surface festooned with dsRNA. This may represent a deliberate strategy to sequester dsRNA released from damaged particles to prevent host cell shutoff.
About this Structure
1H1K is a Single protein structure of sequence from Bluetongue virus. Full crystallographic information is available from OCA.
Reference
The core of bluetongue virus binds double-stranded RNA., Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI, J Virol. 2002 Sep;76(18):9533-6. PMID:12186935
Page seeded by OCA on Thu Feb 21 12:56:21 2008
