2f54
From Proteopedia
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{{STRUCTURE_2f54| PDB=2f54 | SCENE= }} | {{STRUCTURE_2f54| PDB=2f54 | SCENE= }} | ||
===Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity=== | ===Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity=== | ||
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{{ABSTRACT_PUBMED_16600963}} | {{ABSTRACT_PUBMED_16600963}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Hypoproteinemia, hypercatabolic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=109700 109700]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2f54]] is a 10 chain structure of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F54 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Beta-2 microglobulin|Beta-2 microglobulin]] | ||
| + | *[[Major histocompatibility complex|Major histocompatibility complex]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016600963</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Dunn, S M.]] | [[Category: Dunn, S M.]] | ||
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[[Category: Cdr2]] | [[Category: Cdr2]] | ||
[[Category: High affinity]] | [[Category: High affinity]] | ||
| + | [[Category: Immune system]] | ||
[[Category: Ny-eso-1]] | [[Category: Ny-eso-1]] | ||
[[Category: Phage display]] | [[Category: Phage display]] | ||
[[Category: T-cell receptor]] | [[Category: T-cell receptor]] | ||
[[Category: Wild type sequence]] | [[Category: Wild type sequence]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:54:42 2009'' | ||
Revision as of 11:16, 27 July 2012
Contents |
Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity
Template:ABSTRACT PUBMED 16600963
About this Structure
2f54 is a 10 chain structure of Beta-2 microglobulin and Major histocompatibility complex with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Dunn SM, Rizkallah PJ, Baston E, Mahon T, Cameron B, Moysey R, Gao F, Sami M, Boulter J, Li Y, Jakobsen BK. Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity. Protein Sci. 2006 Apr;15(4):710-21. PMID:16600963 doi:15/4/710
