2i0h
From Proteopedia
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{{STRUCTURE_2i0h| PDB=2i0h | SCENE= }} | {{STRUCTURE_2i0h| PDB=2i0h | SCENE= }} | ||
===The structure of p38alpha in complex with an arylpyridazinone=== | ===The structure of p38alpha in complex with an arylpyridazinone=== | ||
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{{ABSTRACT_PUBMED_16945533}} | {{ABSTRACT_PUBMED_16945533}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2i0h]] is a 1 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I0H OCA]. | |
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| + | ==See Also== | ||
| + | *[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016945533</ref><ref group="xtra">PMID:017070898</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mitogen-activated protein kinase]] | [[Category: Mitogen-activated protein kinase]] | ||
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[[Category: Inhibitor design]] | [[Category: Inhibitor design]] | ||
[[Category: Serine/threonine kinase]] | [[Category: Serine/threonine kinase]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 11:19, 27 July 2012
Contents |
The structure of p38alpha in complex with an arylpyridazinone
Template:ABSTRACT PUBMED 16945533
About this Structure
2i0h is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Natarajan SR, Heller ST, Nam K, Singh SB, Scapin G, Patel S, Thompson JE, Fitzgerald CE, O'Keefe SJ. p38 MAP kinase inhibitors. Part 6: 2-arylpyridazin-3-ones as templates for inhibitor design. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5809-13. Epub 2006 Aug 30. PMID:16945533 doi:10.1016/j.bmcl.2006.08.074
- Lahiri SD, Zhang G, Dunaway-Mariano D, Allen KN. Diversification of function in the haloacid dehalogenase enzyme superfamily: The role of the cap domain in hydrolytic phosphoruscarbon bond cleavage. Bioorg Chem. 2006 Dec;34(6):394-409. Epub 2006 Oct 27. PMID:17070898 doi:10.1016/j.bioorg.2006.09.007
