3s2a
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
[[Image:3s2a.png|left|200px]] | [[Image:3s2a.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3s2a", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3s2a| PDB=3s2a | SCENE= }} | {{STRUCTURE_3s2a| PDB=3s2a | SCENE= }} | ||
===Crystal structure of PI3K-gamma in complex with a quinoline inhibitor=== | ===Crystal structure of PI3K-gamma in complex with a quinoline inhibitor=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_21612232}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 21612232 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_21612232}} | {{ABSTRACT_PUBMED_21612232}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3s2a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S2A OCA]. | + | [[3s2a]] is a 1 chain structure of [[Phosphoinositide 3-Kinases]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S2A OCA]. |
| + | |||
| + | ==See Also== | ||
| + | *[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]] | ||
==Reference== | ==Reference== | ||
Revision as of 11:26, 27 July 2012
Contents |
Crystal structure of PI3K-gamma in complex with a quinoline inhibitor
Template:ABSTRACT PUBMED 21612232
About this Structure
3s2a is a 1 chain structure of Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Nishimura N, Siegmund A, Liu L, Yang K, Bryan MC, Andrews KL, Bo Y, Booker SK, Caenepeel S, Freeman DJ, Liao H, McCarter JD, Mullady EL, San Miguel T, Subramanian R, Tamayo N, Wang L, Whittington DA, Zalameda LP, Zhang N, Hughes PE, Norman MH. Phospshoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors: Discovery and Structure-Activity Relationships of a Series of Quinoline and Quinoxaline Derivatives. J Med Chem. 2011 May 25. PMID:21612232 doi:10.1021/jm200386s
