2fvd
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2fvd.png|left|200px]] | [[Image:2fvd.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2fvd", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2fvd| PDB=2fvd | SCENE= }} | {{STRUCTURE_2fvd| PDB=2fvd | SCENE= }} | ||
===Cyclin Dependent Kinase 2 (CDK2) with diaminopyrimidine inhibitor=== | ===Cyclin Dependent Kinase 2 (CDK2) with diaminopyrimidine inhibitor=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_17064073}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 17064073 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_17064073}} | {{ABSTRACT_PUBMED_17064073}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2fvd]] is a 1 chain structure of [[Cell Division Protein Kinase 2]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FVD OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017064073</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
| Line 30: | Line 21: | ||
[[Category: Lukacs, C M.]] | [[Category: Lukacs, C M.]] | ||
[[Category: Cdk2 ligand]] | [[Category: Cdk2 ligand]] | ||
| - | + | [[Category: Transferase]] | |
| - | + | ||
Revision as of 11:31, 27 July 2012
Contents |
Cyclin Dependent Kinase 2 (CDK2) with diaminopyrimidine inhibitor
Template:ABSTRACT PUBMED 17064073
About this Structure
2fvd is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Chu XJ, DePinto W, Bartkovitz D, So SS, Vu BT, Packman K, Lukacs C, Ding Q, Jiang N, Wang K, Goelzer P, Yin X, Smith MA, Higgins BX, Chen Y, Xiang Q, Moliterni J, Kaplan G, Graves B, Lovey A, Fotouhi N. Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-diflu oro-6- methoxyphenyl)methanone (R547), a potent and selective cyclin-dependent kinase inhibitor with significant in vivo antitumor activity. J Med Chem. 2006 Nov 2;49(22):6549-60. PMID:17064073 doi:10.1021/jm0606138
