2fvd

From Proteopedia

Revision as of 11:31, 27 July 2012 (edit) OCA (Talk | contribs) ← Previous diff

Revision as of 11:31, 27 July 2012 (edit) (undo) OCA (Talk | contribs) m (Protected "2fvd" [edit=sysop:move=sysop]) Next diff →

---

Revision as of 11:31, 27 July 2012

proteopedia linkproteopedia link

Template:STRUCTURE 2fvd

Contents 1 Cyclin Dependent Kinase 2 (CDK2) with diaminopyrimidine inhibitor 2 About this Structure 3 See Also 4 Reference

Cyclin Dependent Kinase 2 (CDK2) with diaminopyrimidine inhibitor

Template:ABSTRACT PUBMED 17064073

About this Structure

2fvd is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Cell Division Protein Kinase 2

Reference

• Chu XJ, DePinto W, Bartkovitz D, So SS, Vu BT, Packman K, Lukacs C, Ding Q, Jiang N, Wang K, Goelzer P, Yin X, Smith MA, Higgins BX, Chen Y, Xiang Q, Moliterni J, Kaplan G, Graves B, Lovey A, Fotouhi N. Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-diflu oro-6- methoxyphenyl)methanone (R547), a potent and selective cyclin-dependent kinase inhibitor with significant in vivo antitumor activity. J Med Chem. 2006 Nov 2;49(22):6549-60. PMID:17064073 doi:10.1021/jm0606138