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2f4j

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Image:2f4j.png

Template:STRUCTURE 2f4j

Contents

Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680

Template:ABSTRACT PUBMED 16424036

About this Structure

2f4j is a 1 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Young MA, Shah NP, Chao LH, Seeliger M, Milanov ZV, Biggs WH 3rd, Treiber DK, Patel HK, Zarrinkar PP, Lockhart DJ, Sawyers CL, Kuriyan J. Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680. Cancer Res. 2006 Jan 15;66(2):1007-14. PMID:16424036 doi:http://dx.doi.org/66/2/1007

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OCA

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