2zjh
From Proteopedia
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{{STRUCTURE_2zjh| PDB=2zjh | SCENE= }} | {{STRUCTURE_2zjh| PDB=2zjh | SCENE= }} | ||
===Crystal structure of the human BACE1 catalytic domain in complex with N-(1-benzyl-piperidin-4-yl)-4-mercapto-butyramide=== | ===Crystal structure of the human BACE1 catalytic domain in complex with N-(1-benzyl-piperidin-4-yl)-4-mercapto-butyramide=== | ||
| + | {{ABSTRACT_PUBMED_019284778}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2zjh]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZJH OCA]. | |
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| + | ==See Also== | ||
| + | *[[Beta secretase|Beta secretase]] | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:019284778</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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[[Category: Randal, M.]] | [[Category: Randal, M.]] | ||
[[Category: Romanowski, M J.]] | [[Category: Romanowski, M J.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Bace1]] | [[Category: Bace1]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 21 10:40:09 2009'' | ||
Revision as of 11:35, 27 July 2012
Contents |
Crystal structure of the human BACE1 catalytic domain in complex with N-(1-benzyl-piperidin-4-yl)-4-mercapto-butyramide
Template:ABSTRACT PUBMED 019284778
About this Structure
2zjh is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yang W, Fucini RV, Fahr BT, Randal M, Lind KE, Lam MB, Lu W, Lu Y, Cary DR, Romanowski MJ, Colussi D, Pietrak B, Allison TJ, Munshi SK, Penny DM, Pham P, Sun J, Thomas AE, Wilkinson JM, Jacobs JW, McDowell RS, Ballinger MD. Fragment-based discovery of nonpeptidic BACE-1 inhibitors using tethering. Biochemistry. 2009 Jun 2;48(21):4488-96. PMID:19284778 doi:10.1021/bi900017q
