2c3l
From Proteopedia
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===IDENTIFICATION OF A BURIED POCKET FOR POTENT AND SELECTIVE INHIBITION OF CHK1: PREDICTION AND VERIFICATION=== | ===IDENTIFICATION OF A BURIED POCKET FOR POTENT AND SELECTIVE INHIBITION OF CHK1: PREDICTION AND VERIFICATION=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2c3l]] is a 1 chain structure of [[Serine/threonine protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C3L OCA]. | |
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| + | ==See Also== | ||
| + | *[[Serine/threonine protein kinase|Serine/threonine protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016289938</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Oncology]] | [[Category: Oncology]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
| - | [[Category: Ubl conjugation]] | ||
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Revision as of 11:59, 27 July 2012
Contents |
IDENTIFICATION OF A BURIED POCKET FOR POTENT AND SELECTIVE INHIBITION OF CHK1: PREDICTION AND VERIFICATION
Template:ABSTRACT PUBMED 16289938
About this Structure
2c3l is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Foloppe N, Fisher LM, Francis G, Howes R, Kierstan P, Potter A. Identification of a buried pocket for potent and selective inhibition of Chk1: prediction and verification. Bioorg Med Chem. 2006 Mar 15;14(6):1792-804. Epub 2005 Nov 9. PMID:16289938 doi:10.1016/j.bmc.2005.10.022
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Fisher, L M. | Foloppe, N. | Francis, G. | Howes, R. | Kierstan, P. | Potter, A. | Atp-binding | Cell cycle | Dna damage | Dna repair | Drug design | Kinase | Molecular modeling | Molecular recognition | Nuclear protein | Nucleotide-binding | Oncology | Phosphorylation | Serine/threonine-protein kinase | Transferase
