2c3l
From Proteopedia
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m (Protected "2c3l" [edit=sysop:move=sysop]) |
Revision as of 11:59, 27 July 2012
Contents |
IDENTIFICATION OF A BURIED POCKET FOR POTENT AND SELECTIVE INHIBITION OF CHK1: PREDICTION AND VERIFICATION
Template:ABSTRACT PUBMED 16289938
About this Structure
2c3l is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Foloppe N, Fisher LM, Francis G, Howes R, Kierstan P, Potter A. Identification of a buried pocket for potent and selective inhibition of Chk1: prediction and verification. Bioorg Med Chem. 2006 Mar 15;14(6):1792-804. Epub 2005 Nov 9. PMID:16289938 doi:10.1016/j.bmc.2005.10.022
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Fisher, L M. | Foloppe, N. | Francis, G. | Howes, R. | Kierstan, P. | Potter, A. | Atp-binding | Cell cycle | Dna damage | Dna repair | Drug design | Kinase | Molecular modeling | Molecular recognition | Nuclear protein | Nucleotide-binding | Oncology | Phosphorylation | Serine/threonine-protein kinase | Transferase
