1nhv

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Revision as of 12:58, 27 July 2012

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Template:STRUCTURE 1nhv

Contents 1 Hepatitis C virus RNA polymerase in complex with non-nucleoside analogue inhibitor 2 About this Structure 3 See Also 4 Reference

Hepatitis C virus RNA polymerase in complex with non-nucleoside analogue inhibitor

Template:ABSTRACT PUBMED 12509436

About this Structure

1nhv is a 2 chain structure of Nonstructural protein and RNA polymerase with sequence from Hepatitis c virus subtype 1b. Full crystallographic information is available from OCA.

See Also

• Nonstructural protein
• RNA polymerase

Reference

• Wang M, Ng KK, Cherney MM, Chan L, Yannopoulos CG, Bedard J, Morin N, Nguyen-Ba N, Alaoui-Ismaili MH, Bethell RC, James MN. Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition. J Biol Chem. 2003 Mar 14;278(11):9489-95. Epub 2002 Dec 30. PMID:12509436 doi:10.1074/jbc.M209397200