1kli
From Proteopedia
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===Cofactor-and substrate-assisted activation of factor VIIa=== | ===Cofactor-and substrate-assisted activation of factor VIIa=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1kli]] is a 2 chain structure of [[Factor VIIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KLI OCA]. | |
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| + | ==See Also== | ||
| + | *[[Factor VIIa|Factor VIIa]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012225752</ref><ref group="xtra">PMID:011676542</ref><references group="xtra"/> |
[[Category: Coagulation factor VIIa]] | [[Category: Coagulation factor VIIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Sichler, K.]] | [[Category: Sichler, K.]] | ||
[[Category: Extrinsic coagulation pathway]] | [[Category: Extrinsic coagulation pathway]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Rational drug design]] | [[Category: Rational drug design]] | ||
[[Category: Serine protease activation]] | [[Category: Serine protease activation]] | ||
[[Category: Substrate-assisted catalysis]] | [[Category: Substrate-assisted catalysis]] | ||
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Revision as of 13:00, 27 July 2012
Contents |
Cofactor-and substrate-assisted activation of factor VIIa
Template:ABSTRACT PUBMED 12225752
About this Structure
1kli is a 2 chain structure of Factor VIIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Sichler K, Banner DW, D'Arcy A, Hopfner KP, Huber R, Bode W, Kresse GB, Kopetzki E, Brandstetter H. Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions. J Mol Biol. 2002 Sep 20;322(3):591-603. PMID:12225752
- Dullweber F, Stubbs MT, Musil D, Sturzebecher J, Klebe G. Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition. J Mol Biol. 2001 Oct 26;313(3):593-614. PMID:11676542 doi:http://dx.doi.org/10.1006/jmbi.2001.5062
Categories: Coagulation factor VIIa | Homo sapiens | Arcy, A D. | Banner, D W. | Bode, W. | Brandstetter, H. | Hopfner, K P. | Huber, R. | Kopetzki, E. | Kresse, G B. | Sichler, K. | Extrinsic coagulation pathway | Hydrolase | Rational drug design | Serine protease activation | Substrate-assisted catalysis
