3bf6

(Difference between revisions)

Revision as of 13:23, 27 July 2012

3bf6 is a 3 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Lima LM, Becker CF, Giesel GM, Marques AF, Cargnelutti MT, de Oliveira Neto M, Monteiro RQ, Verli H, Polikarpov I. Structural and thermodynamic analysis of thrombin:suramin interaction in solution and crystal phases. Biochim Biophys Acta. 2009 Jun;1794(6):873-81. Epub 2009 Mar 28. PMID:19332154 doi:10.1016/j.bbapap.2009.03.011
Monteiro RQ, Campana PT, Melo PA, Bianconi ML. Suramin interaction with human alpha-thrombin: inhibitory effects and binding studies. Int J Biochem Cell Biol. 2004 Oct;36(10):2077-85. PMID:15203120 doi:10.1016/j.biocel.2004.03.007
Fernandes RS, Assafim M, Arruda EZ, Melo PA, Zingali RB, Monteiro RQ. Suramin counteracts the haemostatic disturbances produced by Bothrops jararaca snake venom. Toxicon. 2007 Jun 1;49(7):931-8. Epub 2007 Jan 20. PMID:17316730 doi:10.1016/j.toxicon.2007.01.002

@@ Line 1: / Line 1: @@
 [[Image:3bf6.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3bf6", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3bf6|  PDB=3bf6  |  SCENE=  }}
 ===Thrombin:suramin complex===
-<!--
-The line below this paragraph, {{ABSTRACT_PUBMED_19332154}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 19332154 is the PubMed ID number.
--->
 {{ABSTRACT_PUBMED_19332154}}