3jsw
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:3jsw.png|left|200px]] | [[Image:3jsw.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3jsw", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3jsw| PDB=3jsw | SCENE= }} | {{STRUCTURE_3jsw| PDB=3jsw | SCENE= }} | ||
===Human PDE9 in complex with selective inhibitor=== | ===Human PDE9 in complex with selective inhibitor=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_19919087}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 19919087 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_19919087}} | {{ABSTRACT_PUBMED_19919087}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3jsw]] is a 2 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSW OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Phosphodiesterase|Phosphodiesterase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019919087</ref><references group="xtra"/> |
[[Category: 3',5'-cyclic-GMP phosphodiesterase]] | [[Category: 3',5'-cyclic-GMP phosphodiesterase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Liu, S.]] | [[Category: Liu, S.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Cgmp]] | [[Category: Cgmp]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| Line 34: | Line 24: | ||
[[Category: Phosphodiesterase]] | [[Category: Phosphodiesterase]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:31:23 2010'' | ||
Revision as of 13:30, 27 July 2012
Contents |
Human PDE9 in complex with selective inhibitor
Template:ABSTRACT PUBMED 19919087
About this Structure
3jsw is a 2 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Verhoest PR, Proulx-Lafrance C, Corman M, Chenard L, Helal CJ, Hou X, Kleiman R, Liu S, Marr E, Menniti FS, Schmidt CJ, Vanase-Frawley M, Schmidt AW, Williams RD, Nelson FR, Fonseca KR, Liras S. Identification of a brain penetrant PDE9A inhibitor utilizing prospective design and chemical enablement as a rapid lead optimization strategy. J Med Chem. 2009 Dec 24;52(24):7946-9. PMID:19919087 doi:10.1021/jm9015334
