3in3

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{{STRUCTURE_3in3| PDB=3in3 | SCENE= }}
{{STRUCTURE_3in3| PDB=3in3 | SCENE= }}
===Bace1 with Compound 30===
===Bace1 with Compound 30===
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{{ABSTRACT_PUBMED_20045648}}
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==About this Structure==
==About this Structure==
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3IN3 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IN3 OCA].
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[[3in3]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IN3 OCA].
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==See Also==
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*[[Beta secretase|Beta secretase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20045648</ref><references group="xtra"/>
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<ref group="xtra">PMID:020045648</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Olland, A M.]]
[[Category: Olland, A M.]]
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[[Category: Alternative splicing]]
 
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Bace1]]
[[Category: Bace1]]
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[[Category: Inhibitor]]
[[Category: Inhibitor]]
[[Category: Membrane]]
[[Category: Membrane]]
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[[Category: Polymorphism]]
 
[[Category: Protease]]
[[Category: Protease]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 14:12:30 2010''
 

Revision as of 13:33, 27 July 2012

Template:STRUCTURE 3in3

Contents

Bace1 with Compound 30

Template:ABSTRACT PUBMED 20045648

About this Structure

3in3 is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Malamas MS, Barnes K, Johnson M, Hui Y, Zhou P, Turner J, Hu Y, Wagner E, Fan K, Chopra R, Olland A, Bard J, Pangalos M, Reinhart P, Robichaud AJ. Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors. Bioorg Med Chem. 2010 Jan 15;18(2):630-9. Epub 2009 Dec 6. PMID:20045648 doi:10.1016/j.bmc.2009.12.007

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