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1way
From Proteopedia
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[[Image:1way.png|left|200px]] | [[Image:1way.png|left|200px]] | ||
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{{STRUCTURE_1way| PDB=1way | SCENE= }} | {{STRUCTURE_1way| PDB=1way | SCENE= }} | ||
===ACTIVE SITE THROMBIN INHIBITORS=== | ===ACTIVE SITE THROMBIN INHIBITORS=== | ||
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{{ABSTRACT_PUBMED_15658854}} | {{ABSTRACT_PUBMED_15658854}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1way]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WAY OCA]. | + | [[1way]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WAY OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Hirudin]] | + | *[[Hirudin|Hirudin]] |
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015658854</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
[[Category: Calcium-binding]] | [[Category: Calcium-binding]] | ||
| - | [[Category: Direct protein sequencing]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Gamma-carboxyglutamic acid]] | [[Category: Gamma-carboxyglutamic acid]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
| - | [[Category: Hydrolase]] | + | [[Category: Hydrolase-hydrolase inhibitor complex]] |
[[Category: Kringle]] | [[Category: Kringle]] | ||
[[Category: Plasma]] | [[Category: Plasma]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Vitamin k]] | [[Category: Vitamin k]] | ||
Revision as of 13:56, 27 July 2012
Contents |
ACTIVE SITE THROMBIN INHIBITORS
Template:ABSTRACT PUBMED 15658854
About this Structure
1way is a 3 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Hartshorn MJ, Murray CW, Cleasby A, Frederickson M, Tickle IJ, Jhoti H. Fragment-based lead discovery using X-ray crystallography. J Med Chem. 2005 Jan 27;48(2):403-13. PMID:15658854 doi:http://dx.doi.org/10.1021/jm0495778
Categories: Homo sapiens | Thrombin | Cleasby, A. | Frederickson, M. | Hartshorn, M J. | Jhoti, H. | Murray, C W. | Tickle, I J. | Acute phase | Blood coagulation | Calcium-binding | Disease mutation | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase-hydrolase inhibitor complex | Kringle | Plasma | Protease | Serine protease | Vitamin k
