2fqq
From Proteopedia
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===Crystal structure of human caspase-1 (Cys285->Ala, Cys362->Ala, Cys364->Ala, Cys397->Ala) in complex with 1-methyl-3-trifluoromethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (2-mercapto-ethyl)-amide=== | ===Crystal structure of human caspase-1 (Cys285->Ala, Cys362->Ala, Cys364->Ala, Cys397->Ala) in complex with 1-methyl-3-trifluoromethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (2-mercapto-ethyl)-amide=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2fqq]] is a 2 chain structure of [[Caspase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQQ OCA]. | |
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| + | ==See Also== | ||
| + | *[[Caspase|Caspase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016682620</ref><references group="xtra"/> |
[[Category: Caspase-1]] | [[Category: Caspase-1]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Allosteric inhibitor]] | [[Category: Allosteric inhibitor]] | ||
[[Category: Caspase]] | [[Category: Caspase]] | ||
| - | + | [[Category: Hydrolase]] | |
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Revision as of 14:38, 27 July 2012
Contents |
Crystal structure of human caspase-1 (Cys285->Ala, Cys362->Ala, Cys364->Ala, Cys397->Ala) in complex with 1-methyl-3-trifluoromethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (2-mercapto-ethyl)-amide
Template:ABSTRACT PUBMED 16682620
About this Structure
2fqq is a 2 chain structure of Caspase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Scheer JM, Romanowski MJ, Wells JA. A common allosteric site and mechanism in caspases. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7595-600. Epub 2006 May 8. PMID:16682620
