3cid

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Revision as of 14:40, 27 July 2012

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Template:STRUCTURE 3cid

Contents 1 Structure of BACE Bound to SCH726222 2 About this Structure 3 See Also 4 Reference

Structure of BACE Bound to SCH726222

Template:ABSTRACT PUBMED 18468890

About this Structure

3cid is a 2 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Cumming JN, Le TX, Babu S, Carroll C, Chen X, Favreau L, Gaspari P, Guo T, Hobbs DW, Huang Y, Iserloh U, Kennedy ME, Kuvelkar R, Li G, Lowrie J, McHugh NA, Ozgur L, Pan J, Parker EM, Saionz K, Stamford AW, Strickland C, Tadesse D, Voigt J, Wang L, Wu Y, Zhang L, Zhang Q. Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3236-41. Epub 2008 Apr 25. PMID:18468890 doi:http://dx.doi.org/10.1016/j.bmcl.2008.04.050