1nvu
From Proteopedia
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[[Image:1nvu.png|left|200px]] | [[Image:1nvu.png|left|200px]] | ||
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{{STRUCTURE_1nvu| PDB=1nvu | SCENE= }} | {{STRUCTURE_1nvu| PDB=1nvu | SCENE= }} | ||
===Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS=== | ===Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS=== | ||
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{{ABSTRACT_PUBMED_12628188}} | {{ABSTRACT_PUBMED_12628188}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Fibromatosis, gingival OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=182530 182530]], Noonan syndrome 4 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=182530 182530]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1nvu]] is a 3 chain structure of [[GTPase HRas]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NVU OCA]. | |
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| + | ==See Also== | ||
| + | *[[GTPase HRas|GTPase HRas]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012628188</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bar-Sagi, D.]] | [[Category: Bar-Sagi, D.]] | ||
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[[Category: Guanine nucleotide release factor]] | [[Category: Guanine nucleotide release factor]] | ||
[[Category: Proto-oncogene]] | [[Category: Proto-oncogene]] | ||
| - | + | [[Category: Signaling protein]] | |
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Revision as of 14:50, 27 July 2012
Contents |
Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Template:ABSTRACT PUBMED 12628188
About this Structure
1nvu is a 3 chain structure of GTPase HRas with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J. Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS. Cell. 2003 Mar 7;112(5):685-95. PMID:12628188
