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1nvu

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{{Seed}}
 
[[Image:1nvu.png|left|200px]]
[[Image:1nvu.png|left|200px]]
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{{STRUCTURE_1nvu| PDB=1nvu | SCENE= }}
{{STRUCTURE_1nvu| PDB=1nvu | SCENE= }}
===Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS===
===Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS===
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{{ABSTRACT_PUBMED_12628188}}
{{ABSTRACT_PUBMED_12628188}}
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==Disease==
 
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Known disease associated with this structure: Fibromatosis, gingival OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=182530 182530]], Noonan syndrome 4 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=182530 182530]]
 
==About this Structure==
==About this Structure==
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1NVU is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NVU OCA].
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[[1nvu]] is a 3 chain structure of [[GTPase HRas]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NVU OCA].
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==See Also==
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*[[GTPase HRas|GTPase HRas]]
==Reference==
==Reference==
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<ref group="xtra">PMID:12628188</ref><references group="xtra"/>
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<ref group="xtra">PMID:012628188</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bar-Sagi, D.]]
[[Category: Bar-Sagi, D.]]
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[[Category: Guanine nucleotide release factor]]
[[Category: Guanine nucleotide release factor]]
[[Category: Proto-oncogene]]
[[Category: Proto-oncogene]]
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[[Category: Signaling protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:42:10 2009''
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Revision as of 14:50, 27 July 2012

Template:STRUCTURE 1nvu

Contents

Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS

Template:ABSTRACT PUBMED 12628188

About this Structure

1nvu is a 3 chain structure of GTPase HRas with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J. Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS. Cell. 2003 Mar 7;112(5):685-95. PMID:12628188

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