1hjz
From Proteopedia
| Line 4: | Line 4: | ||
==Overview== | ==Overview== | ||
| - | MacroH2A is an unusual histone H2A variant that has an extensive | + | MacroH2A is an unusual histone H2A variant that has an extensive C-terminal tail that comprises approximately two thirds of the protein. The C-terminal non-histone domain of macroH2A is also found in a number of other proteins and has been termed the macro domain. Here we report the crystal structure to 1.7A of AF1521, a protein consisting of a stand-alone macro domain from Archaeoglobus fulgidus. The structure has a mixed alpha/beta fold that closely resembles the N-terminal DNA binding domain of the Escherichia coli leucine aminopeptidase PepA. The structure also shows some similarity to members of the P-loop family of nucleotide hydrolases. |
==About this Structure== | ==About this Structure== | ||
| Line 13: | Line 13: | ||
[[Category: Archaeoglobus fulgidus]] | [[Category: Archaeoglobus fulgidus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Allen, M | + | [[Category: Allen, M D.]] |
| - | [[Category: Buckle, A | + | [[Category: Buckle, A M.]] |
[[Category: Bycroft, M.]] | [[Category: Bycroft, M.]] | ||
| - | [[Category: Cordell, S | + | [[Category: Cordell, S C.]] |
[[Category: Lowe, J.]] | [[Category: Lowe, J.]] | ||
[[Category: MES]] | [[Category: MES]] | ||
| Line 22: | Line 22: | ||
[[Category: histone macroh2a]] | [[Category: histone macroh2a]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:02:00 2008'' |
Revision as of 11:02, 21 February 2008
|
CRYSTAL STRUCTURE OF AF1521 PROTEIN CONTAINING A MACROH2A DOMAIN
Overview
MacroH2A is an unusual histone H2A variant that has an extensive C-terminal tail that comprises approximately two thirds of the protein. The C-terminal non-histone domain of macroH2A is also found in a number of other proteins and has been termed the macro domain. Here we report the crystal structure to 1.7A of AF1521, a protein consisting of a stand-alone macro domain from Archaeoglobus fulgidus. The structure has a mixed alpha/beta fold that closely resembles the N-terminal DNA binding domain of the Escherichia coli leucine aminopeptidase PepA. The structure also shows some similarity to members of the P-loop family of nucleotide hydrolases.
About this Structure
1HJZ is a Single protein structure of sequence from Archaeoglobus fulgidus with as ligand. Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A., Allen MD, Buckle AM, Cordell SC, Lowe J, Bycroft M, J Mol Biol. 2003 Jul 11;330(3):503-11. PMID:12842467
Page seeded by OCA on Thu Feb 21 13:02:00 2008
