2rgu

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[[Image:2rgu.png|left|200px]]
[[Image:2rgu.png|left|200px]]
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{{STRUCTURE_2rgu| PDB=2rgu | SCENE= }}
{{STRUCTURE_2rgu| PDB=2rgu | SCENE= }}
===Crystal structure of complex of human DPP4 and inhibitor===
===Crystal structure of complex of human DPP4 and inhibitor===
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{{ABSTRACT_PUBMED_18052023}}
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==See Also==
==See Also==
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*[[Dipeptidyl peptidase]]
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*[[Dipeptidyl peptidase|Dipeptidyl peptidase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:18052023</ref><references group="xtra"/>
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<ref group="xtra">PMID:018052023</ref><references group="xtra"/>
[[Category: Dipeptidyl-peptidase IV]]
[[Category: Dipeptidyl-peptidase IV]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 15:06, 27 July 2012

Template:STRUCTURE 2rgu

Contents

Crystal structure of complex of human DPP4 and inhibitor

Template:ABSTRACT PUBMED 18052023

About this Structure

2rgu is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Eckhardt M, Langkopf E, Mark M, Tadayyon M, Thomas L, Nar H, Pfrengle W, Guth B, Lotz R, Sieger P, Fuchs H, Himmelsbach F. 8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin -2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes. J Med Chem. 2007 Dec 27;50(26):6450-3. Epub 2007 Dec 1. PMID:18052023 doi:10.1021/jm701280z

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