2rgu
From Proteopedia
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[[Image:2rgu.png|left|200px]] | [[Image:2rgu.png|left|200px]] | ||
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{{STRUCTURE_2rgu| PDB=2rgu | SCENE= }} | {{STRUCTURE_2rgu| PDB=2rgu | SCENE= }} | ||
===Crystal structure of complex of human DPP4 and inhibitor=== | ===Crystal structure of complex of human DPP4 and inhibitor=== | ||
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==See Also== | ==See Also== | ||
- | *[[Dipeptidyl peptidase]] | + | *[[Dipeptidyl peptidase|Dipeptidyl peptidase]] |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018052023</ref><references group="xtra"/> |
[[Category: Dipeptidyl-peptidase IV]] | [[Category: Dipeptidyl-peptidase IV]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] |
Revision as of 15:06, 27 July 2012
Contents |
Crystal structure of complex of human DPP4 and inhibitor
Template:ABSTRACT PUBMED 18052023
About this Structure
2rgu is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Eckhardt M, Langkopf E, Mark M, Tadayyon M, Thomas L, Nar H, Pfrengle W, Guth B, Lotz R, Sieger P, Fuchs H, Himmelsbach F. 8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin -2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes. J Med Chem. 2007 Dec 27;50(26):6450-3. Epub 2007 Dec 1. PMID:18052023 doi:10.1021/jm701280z