1rd3
From Proteopedia
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===2.5A Structure of Anticoagulant Thrombin Variant E217K=== | ===2.5A Structure of Anticoagulant Thrombin Variant E217K=== | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1rd3]] is a 4 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RD3 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015075325</ref><ref group="xtra">PMID:016673263</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: Myles, T.]] | [[Category: Myles, T.]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
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Revision as of 15:16, 27 July 2012
Contents |
2.5A Structure of Anticoagulant Thrombin Variant E217K
Template:ABSTRACT PUBMED 15075325
About this Structure
1rd3 is a 4 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Carter WJ, Myles T, Gibbs CS, Leung LL, Huntington JA. Crystal structure of anticoagulant thrombin variant E217K provides insights into thrombin allostery. J Biol Chem. 2004 Jun 18;279(25):26387-94. Epub 2004 Apr 9. PMID:15075325 doi:http://dx.doi.org/10.1074/jbc.M402364200
- Bode W. The structure of thrombin: a janus-headed proteinase. Semin Thromb Hemost. 2006 Apr;32 Suppl 1:16-31. PMID:16673263 doi:10.1055/s-2006-939551
