2zb2
From Proteopedia
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===Human liver glycogen phosphorylase a complexed with glcose and 5-chloro-N-[4-(1,2-dihydroxyethyl)phenyl]-1H-indole-2-carboxamide=== | ===Human liver glycogen phosphorylase a complexed with glcose and 5-chloro-N-[4-(1,2-dihydroxyethyl)phenyl]-1H-indole-2-carboxamide=== | ||
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{{ABSTRACT_PUBMED_18434170}} | {{ABSTRACT_PUBMED_18434170}} | ||
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- | ==Disease== | ||
- | Known disease associated with this structure: Glycogen storage disease VI OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=232700 232700]] | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[2zb2]] is a 2 chain structure of [[Glycogen Phosphorylase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZB2 OCA]. | |
+ | |||
+ | ==See Also== | ||
+ | *[[Glycogen Phosphorylase|Glycogen Phosphorylase]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018434170</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Phosphorylase]] | [[Category: Phosphorylase]] | ||
[[Category: Katayama, N.]] | [[Category: Katayama, N.]] | ||
[[Category: Onda, K.]] | [[Category: Onda, K.]] | ||
- | [[Category: Acetylation]] | ||
[[Category: Allosteric binding]] | [[Category: Allosteric binding]] | ||
[[Category: Allosteric enzyme]] | [[Category: Allosteric enzyme]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
- | [[Category: Polymorphism]] | ||
[[Category: Pyridoxal phosphate]] | [[Category: Pyridoxal phosphate]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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Revision as of 15:47, 27 July 2012
Contents |
Human liver glycogen phosphorylase a complexed with glcose and 5-chloro-N-[4-(1,2-dihydroxyethyl)phenyl]-1H-indole-2-carboxamide
Template:ABSTRACT PUBMED 18434170
About this Structure
2zb2 is a 2 chain structure of Glycogen Phosphorylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Onda K, Suzuki T, Shiraki R, Yonetoku Y, Negoro K, Momose K, Katayama N, Orita M, Yamaguchi T, Ohta M, Tsukamoto S. Synthesis of 5-chloro-N-aryl-1H-indole-2-carboxamide derivatives as inhibitors of human liver glycogen phosphorylase a. Bioorg Med Chem. 2008 May 15;16(10):5452-64. Epub 2008 Apr 11. PMID:18434170 doi:10.1016/j.bmc.2008.04.010
Categories: Homo sapiens | Phosphorylase | Katayama, N. | Onda, K. | Allosteric binding | Allosteric enzyme | Allosteric site | Carbohydrate metabolism | Disease mutation | Glycogen metabolism | Glycogen storage disease | Glycosyltransferase | Nucleotide-binding | Phosphorylation | Pyridoxal phosphate | Transferase