2zb2

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[[Image:2zb2.png|left|200px]]
[[Image:2zb2.png|left|200px]]
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{{STRUCTURE_2zb2| PDB=2zb2 | SCENE= }}
{{STRUCTURE_2zb2| PDB=2zb2 | SCENE= }}
===Human liver glycogen phosphorylase a complexed with glcose and 5-chloro-N-[4-(1,2-dihydroxyethyl)phenyl]-1H-indole-2-carboxamide===
===Human liver glycogen phosphorylase a complexed with glcose and 5-chloro-N-[4-(1,2-dihydroxyethyl)phenyl]-1H-indole-2-carboxamide===
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{{ABSTRACT_PUBMED_18434170}}
{{ABSTRACT_PUBMED_18434170}}
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==Disease==
 
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Known disease associated with this structure: Glycogen storage disease VI OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=232700 232700]]
 
==About this Structure==
==About this Structure==
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2ZB2 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZB2 OCA].
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[[2zb2]] is a 2 chain structure of [[Glycogen Phosphorylase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZB2 OCA].
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==See Also==
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*[[Glycogen Phosphorylase|Glycogen Phosphorylase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:18434170</ref><references group="xtra"/>
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<ref group="xtra">PMID:018434170</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphorylase]]
[[Category: Phosphorylase]]
[[Category: Katayama, N.]]
[[Category: Katayama, N.]]
[[Category: Onda, K.]]
[[Category: Onda, K.]]
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[[Category: Acetylation]]
 
[[Category: Allosteric binding]]
[[Category: Allosteric binding]]
[[Category: Allosteric enzyme]]
[[Category: Allosteric enzyme]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
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[[Category: Polymorphism]]
 
[[Category: Pyridoxal phosphate]]
[[Category: Pyridoxal phosphate]]
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:29:12 2009''
 

Revision as of 15:47, 27 July 2012

Template:STRUCTURE 2zb2

Contents

Human liver glycogen phosphorylase a complexed with glcose and 5-chloro-N-[4-(1,2-dihydroxyethyl)phenyl]-1H-indole-2-carboxamide

Template:ABSTRACT PUBMED 18434170

About this Structure

2zb2 is a 2 chain structure of Glycogen Phosphorylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Onda K, Suzuki T, Shiraki R, Yonetoku Y, Negoro K, Momose K, Katayama N, Orita M, Yamaguchi T, Ohta M, Tsukamoto S. Synthesis of 5-chloro-N-aryl-1H-indole-2-carboxamide derivatives as inhibitors of human liver glycogen phosphorylase a. Bioorg Med Chem. 2008 May 15;16(10):5452-64. Epub 2008 Apr 11. PMID:18434170 doi:10.1016/j.bmc.2008.04.010

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