3t3m
From Proteopedia
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| - | [[Image:3t3m. | + | [[Image:3t3m.png|left|200px]] |
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{{STRUCTURE_3t3m| PDB=3t3m | SCENE= }} | {{STRUCTURE_3t3m| PDB=3t3m | SCENE= }} | ||
===A Novel High Affinity Integrin alphaIIbbeta3 Receptor Antagonist That Unexpectedly Displaces Mg2+ from the beta3 MIDAS=== | ===A Novel High Affinity Integrin alphaIIbbeta3 Receptor Antagonist That Unexpectedly Displaces Mg2+ from the beta3 MIDAS=== | ||
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{{ABSTRACT_PUBMED_22422993}} | {{ABSTRACT_PUBMED_22422993}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3t3m]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3M OCA]. | + | [[3t3m]] is a 8 chain structure of [[Monoclonal Antibody]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3M OCA]. |
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| + | ==See Also== | ||
| + | *[[Monoclonal Antibody|Monoclonal Antibody]] | ||
==Reference== | ==Reference== | ||
Revision as of 15:53, 27 July 2012
Contents |
A Novel High Affinity Integrin alphaIIbbeta3 Receptor Antagonist That Unexpectedly Displaces Mg2+ from the beta3 MIDAS
Template:ABSTRACT PUBMED 22422993
About this Structure
3t3m is a 8 chain structure of Monoclonal Antibody with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.
See Also
Reference
- Zhu J, Choi WS, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D, Rasmussen M, Aster R, Thomas CJ, Filizola M, Springer TA, Coller BS. Structure-Guided Design of a High-Affinity Platelet Integrin alphaIIbbeta3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS. Sci Transl Med. 2012 Mar 14;4(125):125ra32. PMID:22422993 doi:10.1126/scitranslmed.3003576
