1sl3
From Proteopedia
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Contents |
crystal structue of Thrombin in complex with a potent P1 heterocycle-Aryl based inhibitor
Template:ABSTRACT PUBMED 15163182
About this Structure
1sl3 is a 2 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Young MB, Barrow JC, Glass KL, Lundell GF, Newton CL, Pellicore JM, Rittle KE, Selnick HG, Stauffer KJ, Vacca JP, Williams PD, Bohn D, Clayton FC, Cook JJ, Krueger JA, Kuo LC, Lewis SD, Lucas BJ, McMasters DR, Miller-Stein C, Pietrak BL, Wallace AA, White RB, Wong B, Yan Y, Nantermet PG. Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors. J Med Chem. 2004 Jun 3;47(12):2995-3008. PMID:15163182 doi:10.1021/jm030303e
Categories: Hirudo medicinalis | Homo sapiens | Thrombin | Barrow, J C. | Bohn, D. | Clayton, F C. | Cook, J J. | Glass, K L. | Krueger, J A. | Kuo, L C. | Lewis, S D. | Lucas, B J. | Lundell, G F. | McMasters, D R. | Miller-Stein, C. | Newton, C L. | Pellicore, J M. | Pietrak, B L. | Rittle, K E. | Selnick, H G. | Stauffer, K J. | Vacca, J P. | Williams, P D. | Young, M B. | Blood clotting | Hydrolase-inhibitor complex | Thrombin inhibitor complex
