2hog
From Proteopedia
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[[Image:2hog.png|left|200px]] | [[Image:2hog.png|left|200px]] | ||
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{{STRUCTURE_2hog| PDB=2hog | SCENE= }} | {{STRUCTURE_2hog| PDB=2hog | SCENE= }} | ||
===crystal structure of Chek1 in complex with inhibitor 20=== | ===crystal structure of Chek1 in complex with inhibitor 20=== | ||
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{{ABSTRACT_PUBMED_16978863}} | {{ABSTRACT_PUBMED_16978863}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2hog]] is a 1 chain structure of [[Serine/threonine protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HOG OCA]. | |
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| + | ==See Also== | ||
| + | *[[Serine/threonine protein kinase|Serine/threonine protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016978863</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Chek1]] | [[Category: Chek1]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 16:23, 27 July 2012
Contents |
crystal structure of Chek1 in complex with inhibitor 20
Template:ABSTRACT PUBMED 16978863
About this Structure
2hog is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Fraley ME, Steen JT, Brnardic EJ, Arrington KL, Spencer KL, Hanney BA, Kim Y, Hartman GD, Stirdivant SM, Drakas BA, Rickert K, Walsh ES, Hamilton K, Buser CA, Hardwick J, Tao W, Beck SC, Mao X, Lobell RB, Sepp-Lorenzino L, Yan Y, Ikuta M, Munshi SK, Kuo LC, Kreatsoulas C. 3-(Indol-2-yl)indazoles as Chek1 kinase inhibitors: Optimization of potency and selectivity via substitution at C6. Bioorg Med Chem Lett. 2006 Dec 1;16(23):6049-53. Epub 2006 Sep 15. PMID:16978863 doi:10.1016/j.bmcl.2006.08.118
