1s6q

From Proteopedia

Revision as of 16:37, 27 July 2012 (edit) OCA (Talk | contribs) ← Previous diff

Revision as of 16:37, 27 July 2012 (edit) (undo) OCA (Talk | contribs) m (Protected "1s6q" [edit=sysop:move=sysop]) Next diff →

---

Revision as of 16:37, 27 July 2012

proteopedia linkproteopedia link

Template:STRUCTURE 1s6q

Contents 1 CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R147681 2 About this Structure 3 See Also 4 Reference

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R147681

Template:ABSTRACT PUBMED 15115397

About this Structure

1s6q is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

• Reverse transcriptase

Reference

• Das K, Clark AD Jr, Lewi PJ, Heeres J, De Jonge MR, Koymans LM, Vinkers HM, Daeyaert F, Ludovici DW, Kukla MJ, De Corte B, Kavash RW, Ho CY, Ye H, Lichtenstein MA, Andries K, Pauwels R, De Bethune MP, Boyer PL, Clark P, Hughes SH, Janssen PA, Arnold E. Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variants. J Med Chem. 2004 May 6;47(10):2550-60. PMID:15115397 doi:http://dx.doi.org/10.1021/jm030558s