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1hxb
From Proteopedia
(New page: 200px<br /> <applet load="1hxb" size="450" color="white" frame="true" align="right" spinBox="true" caption="1hxb, resolution 2.30Å" /> '''HIV-1 PROTEINASE CO...) |
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| - | [[Image:1hxb.gif|left|200px]]<br /> | + | [[Image:1hxb.gif|left|200px]]<br /><applet load="1hxb" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="1hxb" size=" | + | |
caption="1hxb, resolution 2.30Å" /> | caption="1hxb, resolution 2.30Å" /> | ||
'''HIV-1 PROTEINASE COMPLEXED WITH RO 31-8959'''<br /> | '''HIV-1 PROTEINASE COMPLEXED WITH RO 31-8959'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
| - | 1HXB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Viruses Viruses] with QNC and DIQ as [http://en.wikipedia.org/wiki/ligands ligands]. The following page contains interesting information on the relation of 1HXB with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb6_1.html HIV-1 Protease]]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http:// | + | 1HXB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Viruses Viruses] with <scene name='pdbligand=QNC:'>QNC</scene> and <scene name='pdbligand=DIQ:'>DIQ</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. The following page contains interesting information on the relation of 1HXB with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb6_1.html HIV-1 Protease]]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXB OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Viruses]] | [[Category: Viruses]] | ||
| - | [[Category: Crowther, R | + | [[Category: Crowther, R L.]] |
| - | [[Category: Graves, B | + | [[Category: Graves, B J.]] |
| - | [[Category: Hatada, M | + | [[Category: Hatada, M H.]] |
[[Category: DIQ]] | [[Category: DIQ]] | ||
[[Category: QNC]] | [[Category: QNC]] | ||
| Line 21: | Line 20: | ||
[[Category: rna-directed dna polymerase]] | [[Category: rna-directed dna polymerase]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:05:47 2008'' |
Revision as of 11:05, 21 February 2008
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HIV-1 PROTEINASE COMPLEXED WITH RO 31-8959
About this Structure
1HXB is a Single protein structure of sequence from Viruses with and as ligands. The following page contains interesting information on the relation of 1HXB with [HIV-1 Protease]. Active as HIV-1 retropepsin, with EC number 3.4.23.16 Full crystallographic information is available from OCA.
Reference
Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere., Krohn A, Redshaw S, Ritchie JC, Graves BJ, Hatada MH, J Med Chem. 1991 Nov;34(11):3340-2. PMID:1956054
Page seeded by OCA on Thu Feb 21 13:05:47 2008
