4emv

(Difference between revisions)

Revision as of 05:48, 1 August 2012

4emv is a 1 chain structure with sequence from Streptococcus pneumoniae ga47373. Full crystallographic information is available from OCA.

Manchester JI, Dussault DD, Rose JA, Boriack-Sjodin PA, Uria-Nickelsen M, Ioannidis G, Bist S, Fleming P, Hull KG. Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5150-6. Epub 2012 Jun 19. PMID:22814212 doi:10.1016/j.bmcl.2012.05.128

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-'''Unreleased structure'''
+[[Image:4emv.jpg|left|200px]]
-The entry 4emv is ON HOLD  until Paper Publication
+{{STRUCTURE_4emv|  PDB=4emv  |  SCENE=  }}
-Authors: Boriack-Sjodin, P.A., Manchester, J., Hull, K.
+===Crystal structure of a topoisomerase ATP inhibitor===
-Description: Crystal structure of a topoisomerase ATP inhibitor
+{{ABSTRACT_PUBMED_22814212}}
+==About this Structure==
+[[4emv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_ga47373 Streptococcus pneumoniae ga47373]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EMV OCA].
+==Reference==
+<ref group="xtra">PMID:022814212</ref><references group="xtra"/>
+[[Category: Streptococcus pneumoniae ga47373]]
+[[Category: Boriack-Sjodin, P A.]]
+[[Category: Hull, K.]]
+[[Category: Manchester, J.]]
+[[Category: Antimicrobial]]
+[[Category: Atp binding]]
+[[Category: Isomerase-isomerase inhibitor complex]]
+[[Category: Protein-inhibitor complex]]
+[[Category: Structure-based drug design]]
+[[Category: Virtual screen]]