This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Forkhead box protein
From Proteopedia
| Line 1: | Line 1: | ||
{{STRUCTURE_3co6| PDB=3co6 | SIZE=400| SCENE= |right|CAPTION=Human FOXO1 complex with DNA, Ca+2 and chloride ions, [[3co6]] }} | {{STRUCTURE_3co6| PDB=3co6 | SIZE=400| SCENE= |right|CAPTION=Human FOXO1 complex with DNA, Ca+2 and chloride ions, [[3co6]] }} | ||
| - | '''Forkhead box proteins''' (FOX) are transcription factors involved in regulation of gene expression. They contain a DNA-binding motif of 80-100 amino acids having a winged-helix shape. For details on individual FOX proteins, see [[FOXP2]] | + | '''Forkhead box proteins''' (FOX) are transcription factors involved in regulation of gene expression. They contain a DNA-binding motif of 80-100 amino acids having a winged-helix shape. For details on individual FOX proteins, see <br /> |
| + | *[[FOXP2]]<br /> | ||
| + | *[[FOXP3]]<br /> | ||
| + | *[[Forkhead Box Protein 3]]<br /> | ||
| + | *[[Forkhead box protein M1]]<br /> | ||
| + | *[[Foxp2 bound specifically to DNA]].<br /> | ||
| + | See also [[Transcription and RNA Processing]]. | ||
==3D structures of FOX== | ==3D structures of FOX== | ||
Revision as of 08:42, 2 August 2012
Template:STRUCTURE 3co6
Forkhead box proteins (FOX) are transcription factors involved in regulation of gene expression. They contain a DNA-binding motif of 80-100 amino acids having a winged-helix shape. For details on individual FOX proteins, see
See also Transcription and RNA Processing.
Contents |
3D structures of FOX
FOXO1
3co6, 3coa – hFOXO1 + DNA – human
FOXO3
2uzk – hFOXO3 DNA-binding domain + DNA
FOXO4
3l2c – hFOXO4 DNA-binding domain + DNA
FOXP1
2kiu – hFOXP1 DNA-binding domain (mutant) - NMR
FOXP2
2a07 – hFOXP2 + DNA
2as5 – hFOXP2 DNA-binding domain + nuclear factor of activated T-cell + DNA
FOXP3
3qrf – hFOXP3 DNA-binding domain + nuclear factor of activated T-cell + DNA
FOXK2
2c6y – hFOXK2 DNA-binding domain + DNA
FOXK1
2a3s, 2d2w – FOXK1 DNA-binding domain – mouse – NMR
FOXM1
3g73 – hFOXM1 DNA-binding domain + DNA
