4fk3

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m (Protected "4fk3" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:4fk3.jpg|left|200px]]
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The entry 4fk3 is ON HOLD
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{{STRUCTURE_4fk3| PDB=4fk3 | SCENE= }}
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Authors: Zhang, Y., Wang, W., Zhang, K.Y.J.
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===B-Raf Kinase V600E Oncogenic Mutant in Complex with PLX3203===
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Description: B-Raf Kinase V600E Oncogenic Mutant in Complex with PLX3203
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{{ABSTRACT_PUBMED_18287029}}
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==About this Structure==
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[[4fk3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3c4d 3c4d]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FK3 OCA].
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==Reference==
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<ref group="xtra">PMID:018287029</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Wang, W.]]
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[[Category: Zhang, K Y.J.]]
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[[Category: Zhang, Y.]]
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[[Category: Atp-binding]]
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[[Category: Kinase-kinase inhibitor complex]]
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[[Category: Oncogenic v600e]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 05:15, 8 August 2012

Image:4fk3.jpg

Template:STRUCTURE 4fk3

B-Raf Kinase V600E Oncogenic Mutant in Complex with PLX3203

Template:ABSTRACT PUBMED 18287029

About this Structure

4fk3 is a 2 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3c4d. Full crystallographic information is available from OCA.

Reference

  • Tsai J, Lee JT, Wang W, Zhang J, Cho H, Mamo S, Bremer R, Gillette S, Kong J, Haass NK, Sproesser K, Li L, Smalley KS, Fong D, Zhu YL, Marimuthu A, Nguyen H, Lam B, Liu J, Cheung I, Rice J, Suzuki Y, Luu C, Settachatgul C, Shellooe R, Cantwell J, Kim SH, Schlessinger J, Zhang KY, West BL, Powell B, Habets G, Zhang C, Ibrahim PN, Hirth P, Artis DR, Herlyn M, Bollag G. Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3041-6. Epub 2008 Feb 19. PMID:18287029

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OCA

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