3tyq
From Proteopedia
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===SAR development and discovery of potent indole-based inhibitors of the hepatitis c virus NS5B polymerase=== | ===SAR development and discovery of potent indole-based inhibitors of the hepatitis c virus NS5B polymerase=== | ||
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Revision as of 10:15, 8 August 2012
SAR development and discovery of potent indole-based inhibitors of the hepatitis c virus NS5B polymerase
Template:ABSTRACT PUBMED 22247956
About this Structure
3tyq is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
Reference
- Chen KX, Lesburg CA, Vibulbhan B, Yang W, Chan TY, Venkatraman S, Velazquez F, Zeng Q, Bennett F, Anilkumar GN, Duca J, Jiang Y, Pinto P, Wang L, Huang Y, Selyutin O, Gavalas S, Pu H, Agrawal S, Feld B, Huang HC, Li C, Cheng KC, Shih NY, Kozlowski JA, Rosenblum SB, Njoroge FG. A Novel Class of Highly Potent Irreversible Hepatitis C Virus (HCV) NS5B Polymerase Inhibitors. J Med Chem. 2012 Jan 16. PMID:22247956 doi:10.1021/jm201322r