1onz
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[1onz]] is a 1 chain structure of | + | [[1onz]] is a 1 chain structure of [[Tyrosine phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONZ OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Proten tyrosine phosphatase|Proten tyrosine phosphatase]] | ||
*[[Tyrosine phosphatase|Tyrosine phosphatase]] | *[[Tyrosine phosphatase|Tyrosine phosphatase]] | ||
Revision as of 11:30, 14 August 2012
Contents |
Oxalyl-aryl-Amino Benzoic acid Inhibitors of PTP1B, compound 8b
Template:ABSTRACT PUBMED 12747781
About this Structure
1onz is a 1 chain structure of Tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Liu G, Szczepankiewicz BG, Pei Z, Janowick DA, Xin Z, Hajduk PJ, Abad-Zapatero C, Liang H, Hutchins CW, Fesik SW, Ballaron SJ, Stashko MA, Lubben T, Mika AK, Zinker BA, Trevillyan JM, Jirousek MR. Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B. J Med Chem. 2003 May 22;46(11):2093-103. PMID:12747781 doi:http://dx.doi.org/10.1021/jm0205696
- Wiesmann C, Barr KJ, Kung J, Zhu J, Erlanson DA, Shen W, Fahr BJ, Zhong M, Taylor L, Randal M, McDowell RS, Hansen SK. Allosteric inhibition of protein tyrosine phosphatase 1B. Nat Struct Mol Biol. 2004 Aug;11(8):730-7. Epub 2004 Jul 18. PMID:15258570 doi:10.1038/nsmb803
Categories: Homo sapiens | Protein-tyrosine-phosphatase | Abad-Zapatero, C. | Ballaron, S J. | Fesik, S W. | Hadjuk, P J. | Hutchins, C W. | Janowich, D A. | Jirousek, M R. | Liang, H. | Liu, G. | Lubben, T. | Mika, A K. | Pei, Z. | Stashko, M A. | Szczepankiewicz, B G. | Trevillyan, J M. | Xin, Z. | Zinker, B A. | Hydrolase | Oxalyl-aryl-benzoic acid compound with napthyl moiety anchor inhibitor | Protein tyrosine phosphatase
