1w7o
From Proteopedia
(New page: 200px<br /> <applet load="1w7o" size="450" color="white" frame="true" align="right" spinBox="true" caption="1w7o, resolution 1.81Å" /> '''CYTOCHROME C3 FROM ...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1W7O is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Desulfomicrobium_baculatum Desulfomicrobium baculatum]] with HEC as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W7O OCA]]. | + | 1W7O is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Desulfomicrobium_baculatum Desulfomicrobium baculatum]] with HEC as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W7O OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: redox-bohr effect]] | [[Category: redox-bohr effect]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:20:08 2007'' |
Revision as of 12:15, 30 October 2007
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CYTOCHROME C3 FROM DESULFOMICROBIUM BACULATUS
Overview
The tetraheme cytochrome c3 isolated from Desulfomicrobium baculatum (DSM, 1743)(Dsmb) was cloned, and the sequence analysis showed that this, cytochrome differs in just three amino acid residues from the cytochrome, c3 isolated from Desulfomicrobium norvegicum (Dsmn): (DsmnXXDsmb) Thr-37, --> Ser, Val-45 --> Ala, and Phe-88 --> Tyr. X-ray crystallography was, used to determine the structure of cytochrome c3 from Dsmb, showing that, it is very similar to the published structure of cytochrome c3 from Dsmn., A detailed thermodynamic and kinetic characterization of these two, tetraheme cytochromes c3 was performed by using NMR and visible, spectroscopy. The results obtained show that the network of, cooperativities between the redox and protonic centers is consistent with, a ... [(full description)]
About this Structure
1W7O is a [Single protein] structure of sequence from [Desulfomicrobium baculatum] with HEC as [ligand]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Proton-assisted two-electron transfer in natural variants of tetraheme cytochromes from Desulfomicrobium Sp., Correia IJ, Paquete CM, Coelho A, Almeida CC, Catarino T, Louro RO, Frazao C, Saraiva LM, Carrondo MA, Turner DL, Xavier AV, J Biol Chem. 2004 Dec 10;279(50):52227-37. Epub 2004 Sep 28. PMID:15456779
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