1inc
From Proteopedia
(New page: 200px<br /><applet load="1inc" size="450" color="white" frame="true" align="right" spinBox="true" caption="1inc, resolution 1.94Å" /> '''CRYSTAL STRUCTURES O...) |
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| - | [[Image:1inc.jpg|left|200px]]<br /><applet load="1inc" size=" | + | [[Image:1inc.jpg|left|200px]]<br /><applet load="1inc" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1inc, resolution 1.94Å" /> | caption="1inc, resolution 1.94Å" /> | ||
'''CRYSTAL STRUCTURES OF THE COMPLEX OF PORCINE PANCREATIC ELASTASE WITH TWO VALINE-DERIVED BENZOXAZINONE INHIBITORS'''<br /> | '''CRYSTAL STRUCTURES OF THE COMPLEX OF PORCINE PANCREATIC ELASTASE WITH TWO VALINE-DERIVED BENZOXAZINONE INHIBITORS'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The crystal structures of porcine pancreatic elastase complexed to two | + | The crystal structures of porcine pancreatic elastase complexed to two similar benzoxazinone inhibitors are reported to 2.09 A and 1.76 A resolution, and refined to conventional R factors of 0.153 and 0.172. |
==About this Structure== | ==About this Structure== | ||
| - | 1INC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa_domestica Sus scrofa domestica] with SO4, CA and ICL as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Pancreatic_elastase Pancreatic elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.36 3.4.21.36] Full crystallographic information is available from [http:// | + | 1INC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa_domestica Sus scrofa domestica] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=ICL:'>ICL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Pancreatic_elastase Pancreatic elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.36 3.4.21.36] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1INC OCA]. |
==Reference== | ==Reference== | ||
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[[Category: hydrolase(serine proteinase)]] | [[Category: hydrolase(serine proteinase)]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:13:34 2008'' |
Revision as of 11:13, 21 February 2008
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CRYSTAL STRUCTURES OF THE COMPLEX OF PORCINE PANCREATIC ELASTASE WITH TWO VALINE-DERIVED BENZOXAZINONE INHIBITORS
Overview
The crystal structures of porcine pancreatic elastase complexed to two similar benzoxazinone inhibitors are reported to 2.09 A and 1.76 A resolution, and refined to conventional R factors of 0.153 and 0.172.
About this Structure
1INC is a Single protein structure of sequence from Sus scrofa domestica with , and as ligands. Active as Pancreatic elastase, with EC number 3.4.21.36 Full crystallographic information is available from OCA.
Reference
Crystal structures of the complex of porcine pancreatic elastase with two valine-derived benzoxazinone inhibitors., Radhakrishnan R, Presta LG, Meyer EF Jr, Wildonger R, J Mol Biol. 1987 Dec 5;198(3):417-24. PMID:3430613
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