1m5i
From Proteopedia
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[[Image:1m5i.png|left|200px]] | [[Image:1m5i.png|left|200px]] | ||
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{{STRUCTURE_1m5i| PDB=1m5i | SCENE= }} | {{STRUCTURE_1m5i| PDB=1m5i | SCENE= }} | ||
===Crystal Structure of the coiled coil region 129-250 of the tumor suppressor gene product APC=== | ===Crystal Structure of the coiled coil region 129-250 of the tumor suppressor gene product APC=== | ||
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- | (as it appears on PubMed at http://www.pubmed.gov), where 12070164 is the PubMed ID number. | ||
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{{ABSTRACT_PUBMED_12070164}} | {{ABSTRACT_PUBMED_12070164}} | ||
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- | ==Disease== | ||
- | Known disease associated with this structure: Adenoma, periampullary OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611731 611731]], Adenomatous polyposis coli OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611731 611731]], Brain tumor-polyposis syndrome 2 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611731 611731]], Colorectal cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611731 611731]], Desmoid disease, hereditary OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611731 611731]], Gardner syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611731 611731]], Gastric cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611731 611731]], Hepatoblastoma OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611731 611731]] | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[1m5i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M5I OCA]. | |
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:012070164</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Single protein]] | ||
[[Category: Cramer, J.]] | [[Category: Cramer, J.]] | ||
[[Category: Mueller, O.]] | [[Category: Mueller, O.]] | ||
[[Category: Tickenbrock, L.]] | [[Category: Tickenbrock, L.]] | ||
[[Category: Vetter, I R.]] | [[Category: Vetter, I R.]] | ||
+ | [[Category: Antitumor protein]] | ||
[[Category: Coiled-coil]] | [[Category: Coiled-coil]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 23:15:29 2008'' |
Revision as of 17:47, 14 August 2012
Crystal Structure of the coiled coil region 129-250 of the tumor suppressor gene product APC
Template:ABSTRACT PUBMED 12070164
About this Structure
1m5i is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Tickenbrock L, Cramer J, Vetter IR, Muller O. The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). Its structure and its interaction with chromosome maintenance region 1 (Crm-1). J Biol Chem. 2002 Aug 30;277(35):32332-8. Epub 2002 Jun 17. PMID:12070164 doi:10.1074/jbc.M203990200